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Wednesday, February 11, 2009

Medical → Dry gangrena

Gangrene is a complication of necrosis characterized by the decay of body tissues, which become black and malodorous. It is caused by infection or ischemia, such as from thrombosis (blocked blood vessel). Dry gangrene begins at the distal part of the limb due to ischemia and often occurs in the toes and feet.

The dark coloration is due to liberation of hemoglobin from hemolyzed red blood cells which is acted upon by hydrogen sulfide produced by the bacteria, resulting in formation of black iron sulfide that remains in the tissues. The line of separation usually brings about complete separation with eventual falling off of the gangrenous tissue if it is not removed surgically.
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